Everything about The Olfactory Mucosa totally explained
The
olfactory mucosa is an organ made up of the
olfactory epithelium and the
lamina propria, or
mucus secreting
glands, behind the epithelium. The mucus protects the olfactory epithelium and allows
odors to dissolve so that they can be detected by
olfactory receptor neurons. In mammals, the olfactory mucosa is located on the roof of the
nasal cavity above and behind the nostrils.
In vertebrates, the olfactory epithelium consists of three basic cell types:
bipolar olfactory receptor neurons; sustentacular cells, a type of supporting cell; and basal cells, the
stem cells that continuously give rise to new olfactory receptor neurons and sustentacular cells.
Cells in the olfactory mucosa have been shown to have a degree of plasticity, and hold potential for therapeutic applications. Such cells have been used in clinical trials for
adult stem cell therapeutic treatments, and successfully harvested for future applications.
Eskitis Institute for Cell and Molecular Therapies
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